王越

来源:赵飞发布时间:2022-10-17浏览次数:2249

王越,教授,博导,理学院医药生物功能材料重点实验室副主任。日本大阪药科大学博士,南京大学配位化学国家重点实验室博士后,美国密歇根大学访问学者。江苏省“青蓝工程”优秀青年骨干教师,江苏省“青蓝工程”中青年学术带头人,国家留学基金委评审专家,教育部学位论文评审专家,江苏省新研企业及工程中心评审专家,多家国际学术期刊客座编辑和审稿人。主持国家及省自然科学基金项目2项,教育部留学回国人员择优项目1项,中央高校基本业务专项基金重点项目2项,“天然药物活性组分与药效”国家重点实验室培育项目1项,配位化学国家重点实验室开放基金1项,重大校企合作项目2项,其他类校企合作项目6项。主要研究方向为:纳米药物及医用先进材料的开发与应用。共发表SCI论文60余篇,申请专利数十项。

联系方式zwy_1115@126.com  办公室:江宁校区理学院A509-3

5年代表性论文

1. Wang, Q. Y., Dong, Z. P., Lou, F. N., Yin, Y. X., Zhang, J. H., Wen, H. N., Lu, T* and Wang, Y.* Phenylboronic ester-modified polymeric nanoparticles for promoting TRP2 peptide antigen delivery in cancer immunotherapy. Drug Delivery, 2022, 29, 2029.

2. Dong, Z. P., Yin, Y. X., Luo, J., Li, B. X., Lou, F. N., Wang, Q. Y., Zhou, Q. F., Ye, B. F.* and Wang, Y.* An FGFR1-Binding Peptide Modified Liposome for siRNA Delivery in Lung Cancer. International Journal of Molecular Sciences, 2022, 23, 8380.

3. Zhao, B. N., Dong, Z. P., Liu, W. X., Lou, F. N., Wang, Q. Y., Hong, H* and Wang, Y.* Co-administration of combretastatin A4 nanoparticles and anti-PD-L1 for synergistic therapy of hepatocellular carcinoma. Journal of Nanobiotechnology, 2021, 19, 124.

4. Zhao, B. N., Dong, Z. P., Wang, Q. Y., Xu, Y. S., Zhang, N. X., Liu, W. X., Lou, F. N. and Wang, Y.* Highly Efficient Mesoporous Core-Shell Structured Ag@SiO2 Nanosphere as an Environmentally Friendly Catalyst for Hydrogenation of Nitrobenzene. Nanomaterials, 2020, 10, 883.5. Wang, Y. Q., Xu, Y. S., Zhang, N. X., Dong, Z. P., Zhao, B. N., Liu L. C., Lu, T. Wang, Y*. Phenylboronic ester-modified anionic micelles for ROS-stimuli response in HeLa cell, Drug Delivery, 2020, 27, 681.

6. Li, M. L., Liu, S. J., Chen, H., Zhou, X. Y., Zhou, J., Zhou, S. X., Yuan, H. L., XU, Q. L., Liu, J., Cheng, K. G., Sun H. B.*, Wang, Y*. and Wen, X. A.* N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies, European Journal of Medicinal Chemistry, 2020, 199, 112279.7. Bao, J. Y., Liu, H. C., Zhi Y. L., Yang, W. Q., Zhang, J. W., Lu, T., Wang, Y* and Lu, S*. Discovery of benzo[d]oxazole derivatives as the potent type-I FLT3-ITD inhibitors. Bioorganic Chemistry, 2020, 94, 103248.8. Dong Z.P., Wang, Q. Y., Huo, M., Zhang N. X., Li B. X., Li, H. M., Xu, Y. S., Chen, M., Hong, H. and Wang Y.* Mannose-Modified Multi-Walled Carbon Nanotubes as a Delivery Nanovector Optimizing the Antigen Presentation of Dendritic Cells, ChemistryOpen, 2019, 8, 915.

9. Wang, Q. Y., Li, H. M., Dong, Z. P., Li, B. X., Huo, M., Lu, T. and Wang, Y.* Peptide-mediated cationic micelles drug-delivery system applied on a VEGFR3-overexpressed tumor. Journal of Materials Chemistry, B, 2019, 7, 1076.

10. Wang, Y., Zhi, Y. L., Jin, Q. M., Lu, S., Lin, G. W., Yuan, H. L., Yang, T. T., Wang, Z. W., Yao, C., Ling, J., Guo, H., Li, T. H., Jin, J. L., Li, B. Q., Zhang, L., Chen, Y. D. * and Lu, T*. Discovery of 4-((7 H-Pyrrolo [2, 3-d] pyrimidin-4-yl) amino)-N-(4-((4-methylpiperazin-1-yl) methyl) phenyl)-1 H-pyrazole-3-carboxamide (FN-1501), an FLT3-and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia. Journal of Medicinal Chemistry, 2018, 61, 1499.

11. Li, B. X., Zhang, L., Zhang, Z., Gao, R., Li, H. M., Dong, Z. P. & Wang, Y*. Physiologically stable F127-GO supramolecular hydrogel with sustained drug release characteristic for chemotherapy and photothermal therapy. RSC Advances, 2018, 8, 1693.12. Li, H. M., Dong, Z. P., Wang, Q. Y., Liu, L. X., Li, B. X., Ma, X. N. and Wang, Y*. De Novo Computational Design for Development of a Peptide Ligand Oriented to VEGFR-3 with High Affinity and Long Circulation. Molecular Pharmaceutics, 2017, 14, 2236.