杜迎翔,男,1966年3月生,药物分析学教授、博士生导师,中国药科大学理学院副院长,全国高等学校新世纪优秀人才,江苏省“333”中青年科学技术带头人,“青蓝工程”江苏省中青年学术带头人、优秀青年骨干教师。中国药科大学药物分析学专业博士研究生毕业(与日本近畿大学联合培养),获博士学位。曾赴日本近畿大学药学部留学,师从国际著名分析化学和药物分析学家、近畿大学药学部学部长Honda教授。主要学术兼职有:国家科技重大专项和863计划评审专家,国家保健食品评审专家,国家科技奖励评审专家,国家自然科学基金评审专家,教育部学位与研究生教育评审专家,教育部高校同行评议专家,江苏省新药和保健食品审评专家,江苏省药学会药物分析专业委员会委员,江苏省生物医学工程学会临床健康医学工程专业委员会委员等。先后入选江苏省高等学校优秀科技创新团队和教育部创新团队。
主要研究方向为药物色谱分析、药物光谱分析、手性药物毛细管电泳分析。已先后在Journal of chromatography A、Electrophoresis、Analytical and Bioanalytical Chemistry、Talanta、European Journal of Medicinal Chemistry、Journal of Pharmaceutical Sciences等国际性或全国性专业杂志上发表研究论文近120篇,其中SCI 40篇(第1或通讯作者SCI论文35篇),单篇SCI影响因子超过3.0的第1或通讯作者论文16篇。主持或作为前3名主要参加者,先后完成或正在承担国家自然科学基金、国家科技重大专项、国家科技支撑计划等省部级以上科研项目和国家新药研制及质量标准等科技开发项目40余项。副主编或参编出版专著、教材16部(由科学出版社、高等教育出版社等出版),其中《分析化学习题集》获全国普通高等学校优秀教材二等奖,《分析化学系列教材》入选江苏省高等学校精品教材。主讲本科、硕士和博士研究生课程8门,其中“分析化学”获江苏省高等学校精品课程、江苏省二类优秀课程和江苏省成人高等教育精品课程,“药学类专业分析化学多模块分层次教学的改革和实践”获江苏省教学成果二等奖。已负责指导博士研究生17人,硕士研究生52人。
近5年主持承担的省部级以上代表性科研项目:
(1)国家自然科学基金面上项目,基于离子液体的毛细管电泳手性拆分新体系研究(2014.1~2017.12)
(2)国家自然科学基金面上项目,毛细管电泳新型抗生素手性选择剂及其离子液体修饰拆分系统的研究(2011.1~2013.12)
(3)全国高等学校新世纪优秀人才支持计划项目,毛细管电泳新型多糖手性选择剂的研制及手性识别机理研究(2007.1~2009.12)
(4)教育部科学技术研究重点项目,大环抗生素毛细管电泳新型手性选择剂研制及新药对映体拆分研究(2009.1~2011.12)
近5年发表的单篇影响因子超过3.0的第1或通讯作者SCI代表论文(*为通讯作者):
(1) Qi Zhang, Yingxiang Du*, Shuaijing Du. Evaluation of ionic liquids-coated carbon nanotubes modified chiral separation system with chondroitin sulfate E as chiral selector in capillary electrophoresis. Journal of Chromatography A, 1339, 185~191, 2014.
(2) Qi Zhang, Yingxiang Du*, Jiaquan Chen, Guangfu Xu, Tao Yu, Xiaoyi Hua, Jinjing Zhang. Investigation of chondroitin sulfate D and chondroitin sulfate E as novel chiral selectors in capillary electrophoresis. Analytical and Bioanalytical Chemistry, 406, 1557~1566, 2014.
(3) Jinjing Zhang, Yingxiang Du*, Qi Zhang, Yuntao Lei. Evaluation of vancomycin-based synergistic system with amino acid ester chiral ionic liquids as additives for enantioseparation of non-steroidal anti-inflamatory drugs by capillary electrophoresis. Talanta, 119, 193~201, 2014.
(4) Jinjing Zhang, Yingxiang Du*, Qi Zhang, Jiaquan Chen, Guangfu Xu, Tao Yu, Xiaoyi Hua. Investigation of the synergistic effect with amino acid-derived chiral ionic liquids as additives for enantiomeric separation in capillary electrophoresis. Journal of Chromatography A, 1316, 119~126, 2013.
(5) Qi Zhang, Yingxiang Du*. Evaluation of the enantioselectivity of glycogen-based synergistic system with amino acid chiral ionic liquids as additives in capillary electrophoresis. Journal of Chromatography A, 1306, 97~103, 2013.
(6) Xiaoyi Hua, Yingxiang Du*, Jiaquan Chen, Guangfu Xu, Tao Yu, Qi Zhang. Evaluation of the enantioselectivity of carbon nanoparticles-modified chiral separation systems using dextrin as chiral selector by capillary electrokinetic chromatography. Electrophoresis, 34, 1901~1907, 2013.
(7) Tao Yu, Yingxiang Du*, Bin Chen. Evaluation of clarithromycin lactobionate as a novel chiral selector for enantiomeric separation of basic drugs in capillary electrophoresis. Electrophoresis, 32, 1898~1905, 2011.
(8) Jiaquan Chen, Yingxiang Du*, Fenxia Zhu, Bin Chen. Evaluation of the enantioselectivity of glycogen-based dual chiral selector systems towards basic drugs in capillary electrophoresis. Journal of Chromatography A, 1217, 7158~7163, 2010.
(9) Bin Chen, Yingxiang Du*. Evaluation of the enantioseparation capability of the novel chiral selector clindamycin phosphate towards basic drugs by micellar electrokinetic chromatography. Journal of Chromatography A, 1217, 1806~1812, 2010.
(10) Bin Chen, Yingxiang Du*, Hao Wang. Study on enantiomeric separation of basic drugs by NACE in methanol-based medium using erythromycin lactobionate as a chiral selector. Electrophoresis, 31, 371~377, 2010.
(11) Jiaquan Chen, Yingxiang Du*, Fenxia Zhu, Bin Chen. Glycogen: A novel branched polysaccharide chiral selector in CE. Electrophoresis, 31, 1044~1050, 2010.
(12) Xiangping Liu, Yingxiang Du*. Study on the binding of chiral drug duloxetine hydrochloride to human serum albumin. European Journal of Medicinal Chemistry, 45, 4043~4049, 2010.
(13) Bin Chen, Yingxiang Du*, Ping Li. Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector. Electrophoresis, 30, 2747~2754, 2009.
Tel: 13401927478, E-mail: yingxiangdu@163.com