刘海春,男,1980年出生,药物化学专业博士,副教授。2006年浙江大学化学专业硕士研究生毕业,2016年获中国药科大学药物化学专业博士学位。2006年4月起任教于理学院基础化学教研室,现任理学院基础化学党支部支部书记。主要承担本科生“基础化学”、“基础化学实验”和研究生“药学信息挖掘技术基础”等课程,主编或参编学术著作和教材3本。
主要研究方向为1) 计算机辅助药物设计;2)人工智能在药物分子设计应用;3)药物分子设计与合成。主持国家自然科学基金面上项目(82073704),国家自然科学基金青年基金(21102181),参与国家自然科学基金、江苏省自然科学基金、中央高校基本科研业务费专项基金重点基础研究项目等多项科研项目。近年来以第一作者或通讯作者在Journal of Chemical Information and Modeling、Molecular Pharmaceutics、Bioorganic Chemistry等专业领域国际著名刊物上发表SCI收录论文30余篇。
联系方式:1020061011@cpu.edu.cn
近年发表的主要论文:
(1) Yang, Yan#; Zhang, Yanmin#; Hua, Yi; Chen, Xingye; Fan, Yuanrong; Wang, Yuchen; Liang, Li; Deng, Chenglong; Lu, Tao*; Chen, Yadong*; Liu, Haichun*, In Silico Design and Analysis of a Kinase-Focused Combinatorial Library Considering Diversity and Quality, Journal of Chemical Information and Modeling, 2020, 60(1): 92-107.
(2) Bao, Jiyin#; Liu, Haichun#; Zhi, Yanle; Yang, Wenqianzi; Zhang, Jiawei; Lu, Tao; Wang, Yue*; Lu, Shuai*, Discovery of benzo[d]oxazole derivatives as the potent type-I FLT3-ITD inhibitors., Bioorganic Chemistry, 2020, 94: 103248.
(3) Fan, Yuanrong#; Zhang, Yanmin#; Hua, Yi; Wang, Yuchen; Zhu, Lu; Zhao, Junnan; Yang, Yan; Chen, Xingye; Lu, Shuai; Lu, Tao; Chen, Yadong*; Liu, Haichun*, Investigation of Machine Intelligence in Compound Cell Activity Classification, Molecular Pharmaceutics, 2019, 16(11): 4472-4484.
(4) Wang, Yuchen#; Liu, Haichun#; Fan, Yuanrong; Chen, Xingye; Yang, Yan; Zhu, Lu; Zhao, Junnan; Chen, Yadong*; Zhang, Yanmin*, In Silico Prediction of Human Intravenous Pharmacokinetic Parameters with Improved Accuracy, Journal of Chemical Information and Modeling, 2019, 59(9): 3968-3980.
(5) Zhang, Yanmin; Zhao, Junnan; Wang, Yuchen; Fan, Yuanrong; Zhu, Lu; Yang, Yan; Chen, Xingye; Lu, Tao; Chen, Yadong*; Liu, Haichun*, Prediction of hERG K plus channel blockage using deep neural networks, Chemical Biology & Drug Design, 2019, 94(5): 1973-1985.
(6) Lu Zhu, Junnan Zhao, Yanmin Zhang, Weineng Zhou, Linfeng Yin,Yuchen Wang, Yuanrong Fan,Yadong Chen*, Haichun Liu*. ADME properties evaluation in drug discovery: in silico prediction of blood–brain partitioning, Molecular Diversity, 2018, 22, 979–990