1.Yuqin Zhu,Yuxiang Ma, Weidong Zu, Jianing Song, Hua Wang, You Zhong, Hongmei Li, Yanmin Zhang, Qianqian Gao, Bo, Kong, Junyu Xu, Fei Jang, Xinren Wang, Shuwen Li, Chenhe Liu, Haichun Liu, Tao Lu*, and Yadong Chen*. Identification of N-phenyl-7H-pyrrolo[2,3-d] pyrimidin-4-amine Derivatives as Novel, Potent, and Selective NF-κB Inducing Kinase (NIK) Inhibitors for the Treatment of Psoriasis，J. Med. Chem. 2020, 63, 13, 6748–6773.
2.Yan Yang, Yanmin Zhang, Yi Hua, Xingye Chen, Yuanrong Fan, Yuchen Wang, Li Liang, Chenglong Deng, Tao Lu*, Yadong Chen* and Haichun Liu*. In Silico Design and Analysis of a Kinase-Focused Combinatorial Library Considering Diversity and Quality, J. Chem. Inf. Model. 2020,60:92-107
3.Fei Jiang, Qinghua Hu, Zhimin Zhang, Hongmei Li, Huili Li, Dewei Zhang, Hanwen Li, Yu Ma, Jingjing Xu, Haifang Chen, Yong Cui, Yanle Zhi, Yanmin Zhang, Junyu Xu, Jiapeng Zhu*, Tao Lu* and Yadong Chen*. Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis, J. Med. Chem. 2019,62:11080-11107
4.Hao Heng, Zhijie Wang, Hongmei Li, Yatian Huang, Qingyuan Lan, Xiaoxing Guo, Liang Zhang, Yanle Zhi, Jiongheng Cai, Tianren Qin, Li Xiang, Shuxian Wang, Yadong Chen*, Tao Lu*, Shuai Lu*. Combining structure- and property-based optimization to identify selective FLT3-ITD inhibitors with good antitumor efficacy in AML cell inoculated mouse xenograft model, Eur. J. Med. Chem. 2019,176:248-267
5.Yuanrong Fan, Yanmin Zhang, Yi Hua, Yuchen Wang, Lu Zhu, Junnan Zhao, Yan Yang, Xingye Chen, Shuai Lu, Tao Lu, Yadong Chen* and Haichun Liu*. Investigation of Machine Intelligence in Compound Cell Activity Classification, Mol. Pharm. 2019,16:4472-4484.
6.Yuchen Wang, Haichun Liu, Yuanrong Fan, Xingye Chen, Yan Yang, Lu Zhu, Junnan Zhao, Yadong Chen* andYanmin Zhang*. In Silico Prediction of Human Intravenous Pharmacokinetic Parameters with Improved Accuracy, J. Chem. Inf. Model 2019,59:3968-3980 .
7.Xingye Chen, Haichun Liu, Wuchen Xie, Yan Yang, Yuchen Wang, Yuanrong Fan, Yi Hua, Lu Zhu, Junnan Zhao, Yadong Chen* and Yanmin Zhang*. Investigation of Crystal Structures in StructureBased Virtual Screening for Protein Kinase Inhibitors, J. Chem. Inf. Model. 2019,59:5244-5262
8.Yue Wang, Yanle Zhi, Qiaomei Jin, Shuai Lu, Guowu Lin, Haoliang Yuan, Taotao Yang, Zhanwei Wang, Chao Yao, Jun Ling, Hao Guo, Tonghui Li, Jianlin Jin, Baoquan Li, Li Zhang, Yadong Chen*, Tao Lu*. Discovery of 4((7HPyrrolo[2,3d]pyrimidin-4-yl)amino)N(4-((4-methylpiperazin-1-yl)methyl)phenyl)1Hpyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia, J. Med. Chem. 2018,61:1499-1518 .
9.Li Zhang, Jingyun Zhao, Beichen Zhang, Tao Lu*, Yadong Chen*. Discovery of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as novel, potent and selective c-Met kinase inhibitors: Synthesis, SAR study, and biological activity, Eur. J. Med. Chem. 2018,150:809-816
10.Yanmin Zhang, Danfeng Zhang, Haozhong Tian, Yu Jiao, Zhihao Shi, Ting Ran, Haichun Liu, Shuai Lu, Anyang Xu, Xin Qiao, Jing Pan, Lingfeng Yin, Weineng Zhou, Tao Lu*, Yadong Chen*. Identification of Covalent Binding Sites Targeting Cysteines Based on Computational Approaches, Mol. Pharm. 2016,13:3106-3118